According to the Alzheimer's Association, the number of people diagnosed with this debilitating disease is on the rise. It is expected that by the year 2050 almost 14 million people will be living with the condition known to rob people of their memory and impose anxiety and confusion.
Presently, over 5 million people suffer the effects of this disease that is now known as the 7th leading cause of death in our country. It is estimated that over $148 billion is spent each year treating this disease.
There are no pharmaceutical options available to treat, halt or reverse the symptoms of Alzheimer's disease. Drugs being created now are made to reduce the amyloid plaques, made from a protein called Amyloid B (AB) that build up on the brain. These are a trademark of the disease.
However, recent studies reveal that small clumps of AB call oligomers appear years before the plaques even start to develop. The molecular structure of these oligomers is very different from AB.
Further, they found that drugs designed to destroy amyloid plaques have no effect on oligomers. This could explain why experimental Alzheimer's drugs have failed; they are focused on plaques, not their precursor, oligomers.
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